Inflammatory Myopathies

Myositis - A physicians guide to the inflammatory myopathies

  • Polymyositis

  • Dermatomyositis

  • Juvenile Dermatomyositis

  • Inclusion Body Myositis

The Myositis Association is a support organisation based in the USA. They have created a resource for doctors explaining the different inflammatory myopathies covering the basics, signs and symptoms, causes, prognosis, affected populations, diagnosis and treatment - click here for the booklet.

Diagnosis Criteria

Reaching an accurate diagnosis is often a long and frustrating process for myositis patients and their doctors. Because myositis is a rare disease, many people are misdiagnosed for years, or remain undiagnosed, without a name or explanation for their condition.

The following diagnostic criteria may be used as a guide to establish a specific diagnosis.

Sourced from: http://www.myositis.org/for-health-professionals/diagnostic-criteria March 2015

Current management of dermatomyosits

Vermaak, E., & McHugh, N. (2012). Current management of dermatomyositis.International Journal of Clinical Rheumatology, 7(2), 197-215.

Dermatomyositis (DM) is a rare chronic autoimmune condition characterized by proximal muscle weakness, characteristic skin lesions and frequently, specific autoantibodies. Involvement of other organ systems, particularly the lungs, is usual and the condition is associated with malignancy in a significant proportion. The morbidity and mortality associated with DM remains high, despite the availability of a large number of therapeutic agents. Over the recent years, considerable progress has been made in the diagnosis and classification of these patients, particularly in the area of myositis-specific antibodies, which has provided further insight into the etiopathogenesis of this complex disease. Advances made in imaging techniques, especially MRI, have enhanced the diagnostic pathway in DM and provided novel means of monitoring disease activity and response to treatment. Although a number of exciting therapeutic trials are underway, the evidence base for the treatment of DM is found wanting. The aim of this review is to give an update on the approach to management of DM.Click here for full text.

Treatment of dermatomyositis and polymyositis

Idiopathic inflammatory myositis is a group of acquired conditions characterized by inflammation of skeletal muscles. Bohan and Peter proposed that these conditions be divided into primary idiopathic polymyositis, primary idiopathic dermatomyositis, dermatomyositisu polymyositis associated with neoplasia, childhood dermatomyositisupolymyositis, dermatomyositisupolymyositis associated with vasculitis, and polymyositisu dermatomyositis associated with collagen vascular disease. To be taken to the full text article please  click here

188th ENMC International Workshop: Inclusion Body Myositis, 2-4 December 2011

Naarden, The Netherlands M.R. Rose, and ENMC IBM Working Group, Dept of Neurology, Kings College Hospital, Denmark Hill, London SE5 9RS, United Kingdom Received 14 June 2013; received in revised form 13 August 2013; accepted 19 August 2013

Click here for the full text article